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Your translated search: malonyl-CoA = 455 reactions were found.
State Icon Reaction EC-Number Conf. maximal confidence score from EnzymeDetector PW
H+ + 3-hydroxybenzoyl-CoA + malonyl-CoA <=> CO2 + 2,3',4,6-tetrahydroxybenzophenone + CoA 2.3.1.151 2,3',4,6-tetrahydroxybenzophenone synthase
–
M
isovaleryl-CoA + malonyl-CoA + H+ <=> phloroisovalerophenone + CO2 + CoA 2.3.1.156 phloroisovalerophenone synthase
2.3.1.220 2,4,6-trihydroxybenzophenone synthase
–
–
M
H+ + malonyl-CoA <=> CO2 + acetyl-CoA 2.3.1.226 carboxymethylproline synthase
2.3.1.74 chalcone synthase
4.1.1.87 malonyl-S-ACP decarboxylase
4.1.1.9 malonyl-CoA decarboxylase
–
–
–
–
BMK
3,4-dichloroaniline + malonyl-CoA <=> N-(3,4-dichlorophenyl)-malonamate + CoA 2.3.1.114 3,4-dichloroaniline N-malonyltransferase
–
biochanin_A_7-O-beta-D-glucopyranoside + malonyl-CoA <=> biochanin_A-7-O-glucoside-6''''-malonate + CoA 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase
–
MK
flavonol-3-O-beta-D-glucoside + malonyl-CoA + H+ <=> flavonol_3-O-(6-O-malonyl-beta-D-glucoside) + CoA 2.3.1.116 flavonol-3-O-beta-glucoside O-malonyltransferase
–
N-methylanthraniloyl-CoA + malonyl-CoA <=> CO2 + 1,3-dihydroxy-N-methylacridone + CoA 2.3.1.159 acridone synthase
–
MK
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> 6-Methylsalicylate + CoA + CO2 + NADP+ + H2O 2.3.1.165 6-methylsalicylic-acid synthase
–
MK
malonyl-CoA + [acyl-carrier_protein] <=> CoA + malonyl-[acyl-carrier_protein] 2.3.1
2.3.1.39 [acyl-carrier-protein] S-malonyltransferase
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
BMK
H+ + 4-coumaroyl-CoA + malonyl-CoA <=> naringenin_chalcone + CO2 + CoA 2.3.1.159 acridone synthase
2.3.1.74 chalcone synthase
–
–
MK
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> fatty_acid + CoA + CO2 + NADP+ 2.3.1.38 [acyl-carrier-protein] S-acetyltransferase
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
K
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> stearoyl-CoA + CoA + CO2 + NADP+ 2.3.1.86 fatty-acyl-CoA synthase system
–
K
H+ + 4-coumaroyl-CoA + malonyl-CoA <=> resveratrol + CoA + CO2 2.3.1.146 pinosylvin synthase
2.3.1.95 trihydroxystilbene synthase
–
–
MK
malonyl-CoA + cinnamoyl-CoA + H+ <=> CoA + pinosylvin + CO2 2.3.1.146 pinosylvin synthase
2.3.1.95 trihydroxystilbene synthase
–
–
MK
anthranilate + malonyl-CoA <=> N-malonylanthranilate + CoA 2.3.1.113 anthranilate N-malonyltransferase
–
D-tryptophan + malonyl-CoA <=> H+ + N2-malonyl-D-tryptophan + CoA 2.3.1.112 D-tryptophan N-malonyltransferase
–
acetyl-CoA + malonate <=> acetate + malonyl-CoA 2.1.3.10 malonyl-S-ACP:biotin-protein carboxyltransferase
2.8.3.3 malonate CoA-transferase
–
–
BK
H+ + 4-coumaroyl-CoA + malonyl-CoA + NADPH <=> isoliquiritigenin + CoA + CO2 + NADP+ + H2O 2.3.1.170 6'-deoxychalcone synthase
–
MK
malonyl-CoA + an_anthocyanidin_3-O-beta-D-glucoside <=> CoA + an_anthocyanidin_3-O-(6-O-malonyl-beta-D-glucoside) 2.3.1.171 anthocyanin 6''-O-malonyltransferase
–
pelargonidin_3-O-(6-caffeoyl-beta-D-glucoside)_5-O-beta-D-glucoside + malonyl-CoA <=> CoA + 4'''-demalonylsalvianin 2.3.1.172 anthocyanin 5-O-glucoside 6'''-O-malonyltransferase
–
MK
benzoyl-CoA + malonyl-CoA + H+ <=> biphenyl-3,4-diol + CoA + CO2 2.3.1.177 3,5-dihydroxybiphenyl synthase
–
M
malonate_semialdehyde + CoA + NADP+ <=> malonyl-CoA + NADPH + H+ 1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
1.2.1.75 malonyl-CoA reductase (malonate semialdehyde-forming)
–
–
BMK
acetyl-CoA + malonyl-CoA + H+ <=> acetoacetyl-CoA + CoA + CO2 2.3.1.194 acetoacetyl-CoA synthase
–
hexanoyl-CoA + malonyl-CoA + H+ <=> 3,5,7-trioxododecanoyl-CoA + CoA + CO2 2.3.1.206 3,5,7-trioxododecanoyl-CoA synthase
–
K
2-hydroxybenzoyl-CoA + malonyl-CoA + H+ <=> 4-Hydroxycoumarin + CoA + CO2 2.3.1.151 2,3',4,6-tetrahydroxybenzophenone synthase
2.3.1.177 3,5-dihydroxybiphenyl synthase
2.3.1.208 4-hydroxycoumarin synthase
–
–
–
M
4-coumaroyl-CoA + malonyl-CoA + H2O + H+ <=> CoA + bisdemethoxycurcumin + CO2 2.3.1.211 bisdemethoxycurcumin synthase
–
K
H+ + 4-coumaroyl-CoA + malonyl-CoA + H2O <=> 4-hydroxybenzalacetone + CO2 + CoA 2.3.1.212 benzalacetone synthase
–
BM
4'''-demalonylsalvianin + malonyl-CoA <=> salvianin + CoA 2.3.1.214 pelargonidin 3-O-(6-caffeoylglucoside) 5-O-(6-O-malonylglucoside) 4'''-malonyltransferase
2.3.1.224 acetyl-CoA-benzylalcohol acetyltransferase
–
–
MK
H+ + malonyl-CoA <=> 5,7-dihydroxy-2-methyl-4H-chromen-4-one + CoA + CO2 + H2O 2.3.1.216 5,7-dihydroxy-2-methylchromone synthase
–
M
H+ + feruloyl-CoA + malonyl-CoA <=> feruloylacetyl-CoA + CoA + CO2 2.3.1.218 phenylpropanoylacetyl-CoA synthase
–
MK
H+ + 4-coumaroyl-CoA + malonyl-CoA <=> (4-coumaroyl)acetyl-CoA + CoA + CO2 2.3.1.218 phenylpropanoylacetyl-CoA synthase
–
MK
benzoyl-CoA + malonyl-CoA + H+ <=> 2,4,6-trihydroxybenzophenone + CoA + CO2 2.3.1.151 2,3',4,6-tetrahydroxybenzophenone synthase
2.3.1.177 3,5-dihydroxybiphenyl synthase
2.3.1.220 2,4,6-trihydroxybenzophenone synthase
2.3.1.74 chalcone synthase
–
–
–
–
BM
hexanoyl-[acyl-carrier_protein] + malonyl-CoA + H+ <=> norsolorinic_acid_anthrone + [acyl-carrier_protein] + CoA + CO2 + H2O 2.3.1.221 noranthrone synthase
–
MK
H+ + L-pyrroline-5-carboxylate + malonyl-CoA + H2O <=> (2S,5S)-5-carboxymethylproline + CoA + CO2 2.3.1.226 carboxymethylproline synthase
–
BMK
malonyl-CoA + H+ <=> 1,3,6,8-Tetrahydroxynaphthalene + CO2 + CoA + H2O 2.3.1.233 1,3,6,8-tetrahydroxynaphthalene synthase
–
M
malonyl-CoA + H+ <=> tetracenomycin_F2 + CoA + CO2 + H2O 2.3.1.235 tetracenomycin F2 synthase
–
B
acetyl-CoA + malonyl-CoA + H+ + NADPH <=> 5-methyl-1-naphthoate + CoA + CO2 + H2O + NADP+ 2.3.1.236 5-methylnaphthoic acid synthase
–
malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> 10-deoxymethynolide + CoA + CO2 + H2O + NADP+ 2.3.1.239 10-deoxymethynolide synthase
–
MK
malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> narbonolide + CoA + CO2 + H2O + NADP+ 2.3.1.240 narbonolide synthase
–
MK
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> 2-hydroxy-5-methyl-1-naphthoate + CoA + CO2 + H2O + NADP+ 2.3.1.237 neocarzinostatin naphthoate synthase
–
K
malonyl-CoA + H+ <=> 3,5-dihydroxyphenylacetyl-CoA + CoA + CO2 + H2O 2.3.1.246 3,5-dihydroxyphenylacetyl-CoA synthase
–
K
malonyl-CoA + H+ <=> phloroglucinol + CO2 + CoA 2.3.1.253 phloroglucinol synthase
–
malonamoyl-[OxyC_acyl-carrier_protein] + malonyl-CoA + H+ <=> 18-carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[OxyC_acyl-carrier_protein] + CO2 + CoA 2.3.1.260 tetracycline polyketide synthase
–
M
4-hydroxybenzoyl-[4-hydroxyphenylalkanoate_synthase] + malonyl-CoA + NADPH + H+ <=> 17-(4-hydroxyphenyl)heptadecanoyl-[4-hydroxyphenylalkanoate_synthase] + CoA + CO2 + NADP+ + H2O 2.3.1.261 (4-hydroxyphenyl)alkanoate synthase
–
M
2-aminobenzoyl-CoA + malonyl-CoA + H+ <=> 2-aminobenzoylacetyl-CoA + CO2 + CoA 2.3.1.262 anthraniloyl-CoA anthraniloyltransferase
–
isobutyryl-CoA + malonyl-CoA + H+ <=> phloroisobutyrophenone + CO2 + CoA 2.3.1.156 phloroisovalerophenone synthase
2.3.1.220 2,4,6-trihydroxybenzophenone synthase
–
–
M
malonyl-CoA + NADPH + NADH + H+ <=> (2E,5S,6E,8E,10E)-5-hydroxydodeca-2,6,8,10-tetraenal + CoA + CO2 + NADP+ + NAD+ + H2O 2.3.1.281 5-hydroxydodecatetraenal polyketide synthase
–
M
4-nitrobenzoyl-CoA + malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> demethylluteothin + CO2 + CoA + NADP+ + H2O 2.3.1.289 aureothin polyketide synthase system
–
4-nitrobenzoyl-CoA + (S)-methylmalonyl-CoA + malonyl-CoA + NADPH + H+ <=> demethyldeoxyspectinabilin + CO2 + CoA + NADP+ + H2O 2.3.1.290 spectinabilin polyketide synthase system
–
19-(4-hydroxyphenyl)nonadecanoyl-[(phenol)carboxyphthiodiolenone_synthase] + malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> C37-(phenol)carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone_synthase] + CO2 + CoA + NADP+ + H2O 2.3.1.292 (phenol)carboxyphthiodiolenone synthase
–
M
17-(4-hydroxyphenyl)heptadecanoyl-[(phenol)carboxyphthiodiolenone_synthase] + malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> C35-(phenol)carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone_synthase] + CO2 + CoA + NADP+ + H2O 2.3.1.292 (phenol)carboxyphthiodiolenone synthase
–
M
ATP + acetyl-CoA + HCO3- <=> ADP + phosphate + malonyl-CoA + H+ 6.4.1.2 acetyl-CoA carboxylase
6.4.1.3 propionyl-CoA carboxylase
6.4.1.4 methylcrotonoyl-CoA carboxylase
–
–
–
BMK
ATP + alpha,omega-dicarboxylate + CoA <=> malonyl-CoA + AMP + diphosphate 6.2.1
6.2.1.23 dicarboxylate---CoA ligase
–
–
MK
formononetin_7-O-glucoside + malonyl-CoA <=> formononetin-7-O-glucoside-6''''-malonate + CoA 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase
–
MK
genistin + malonyl-CoA <=> genistein-7-O-glucosyl-6''-O-malonate + CoA 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase
–
MK
daidzin + malonyl-CoA <=> daidzein-7-O-glucosyl-6''-O-malonate + CoA 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase
–
MK
(-)-maackiain_3-O-beta-D-glucoside + malonyl-CoA <=> (-)-maackiain-3-O-glucoside-6''''-malonate + CoA 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase
–
MK
apigenin_7-O-glucoside + malonyl-CoA <=> apigenin_7-O-(6-O-malonylglucoside) + CoA 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase
–
M
H+ + acetyl-CoA + malonyl-CoA <=> Triacetate_lactone + CoA + CO2 2.3.1
2.3.1.151 2,3',4,6-tetrahydroxybenzophenone synthase
2.3.1.39 [acyl-carrier-protein] S-malonyltransferase
2.3.1.74 chalcone synthase
–
–
–
–
M
H+ + phenylpropionyl-CoA + malonyl-CoA <=> CO2 + dihydropinosylvin + CoA 2.3.1.146 pinosylvin synthase
–
M
malonyl-CoA + 3-hydroxy-3-methylglutarate <=> malonate + (S)-3-hydroxy-3-methylglutaryl-CoA 2.8.3.13 succinate---hydroxymethylglutarate CoA-transferase
–
delphinidin_3-O-beta-D-glucoside + malonyl-CoA <=> delphinidin_3-O-(6''''-O-malonyl)-beta-glucoside + CoA 2.3.1.171 anthocyanin 6''-O-malonyltransferase
–
MK
cyanidin_3-O-beta-D-glucoside + malonyl-CoA <=> cyanidin-3-O-(6-O-malonyl-beta-D-glucoside) + CoA 2.3.1.171 anthocyanin 6''-O-malonyltransferase
–
MK
pelargonidin_3-O-beta-D-glucoside + malonyl-CoA + H+ <=> pelargonidin_3-O-(6-O-malonyl-beta-D-glucoside) + CoA 2.3.1.171 anthocyanin 6''-O-malonyltransferase
–
MK
shisonin + malonyl-CoA <=> malonylshisonin + CoA 2.3.1.172 anthocyanin 5-O-glucoside 6'''-O-malonyltransferase
–
MK
4-coumaroyl-CoA + malonyl-CoA + H+ <=> 4-hydroxy-6-[(E)-2-(4-hydroxyphenyl)ethenyl]-2H-pyran-2-one + CO2 + CoA 2.3.1.151 2,3',4,6-tetrahydroxybenzophenone synthase
2.3.1.212 benzalacetone synthase
2.3.1.M47
–
–
–
M
cinnamoyl-CoA + malonyl-CoA + H+ <=> 4-hydroxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one + CO2 + CoA 2.3.1.151 2,3',4,6-tetrahydroxybenzophenone synthase
2.3.1.211 bisdemethoxycurcumin synthase
2.3.1.M86
–
–
–
malonyl-CoA + stearoyl-CoA + H+ <=> 3-oxo-arachidoyl-CoA + CO2 + CoA 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
M
hexanoyl-CoA + malonyl-CoA + H2O <=> 4-hydroxy-6-pentyl-2H-pyran-2-one + CoA + CO2 + H2O 2.3.1
2.3.1.233 1,3,6,8-tetrahydroxynaphthalene synthase
2.3.1.74 chalcone synthase
–
–
–
malonyl-CoA + palmitoyl-CoA + H+ <=> 3-oxostearoyl-CoA + CO2 + CoA 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
MK
malonyl-CoA + cinnamoyl-CoA + H+ <=> pinocembrin_chalcone + CoA + CO2 2.3.1
2.3.1.74 chalcone synthase
–
–
K
behenoyl-CoA + malonyl-CoA <=> a_very-long-chain_3-oxoacyl-CoA + CO2 + CoA 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
K
carboxybiotin-carboxyl-carrier_protein + acetyl-CoA <=> biotin-carboxyl-carrier_protein + malonyl-CoA 2.1.3.15 acetyl-CoA carboxytransferase
6.4.1.2 acetyl-CoA carboxylase
–
–
B
acetyl-CoA + oxaloacetate <=> malonyl-CoA + pyruvate 2.1.3.1 methylmalonyl-CoA carboxytransferase
–
K
malonyl-CoA + quercetin_3-O-alpha-D-glucopyranoside <=> CoA + quercetin_3-O-(6-O-malonyl-beta-D-glucoside) 2.3.1.116 flavonol-3-O-beta-glucoside O-malonyltransferase
2.3.1.171 anthocyanin 6''-O-malonyltransferase
–
–
K
acetyl-CoA + 7 malonyl-CoA + 7 NADH + 7 NADPH + 14 H+ <=> palmitoyl-CoA + 7 CoA + 7 CO2 + 7 NAD+ + 7 NADP+ + 7 H2O 2.3.1
2.3.1.86 fatty-acyl-CoA synthase system
–
–
K
apiin + malonyl-CoA <=> apigenin_7-O-apiosylglucoside_-6''''-O-malonylester + CoA 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase
–
K
dihydro-4-coumaroyl-CoA + malonyl-CoA + H+ <=> phloretin + CoA + CO2 2.3.1.74 chalcone synthase
–
MK
2-aminobenzoyl-CoA + malonyl-CoA + H+ <=> 4-hydroxy-2-methylquinoline + CoA + CO2 2.3.1
–
MK
malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ + (2S)-ethylmalonyl-CoA <=> tylactone + CoA + CO2 + H2O + NADP+ 2.3.1
–
MK
cyanidin-3-O-(6-O-malonyl-beta-D-glucoside) + malonyl-CoA <=> cyanidin_3-O-(3'',6''''-O-dimalonyl-beta-glucopyranoside) + CoA 2.3.1
–
MK
malonyl-CoA + L-glutamine + ATP + H2O <=> Malonamoyl-CoA + L-glutamate + AMP + diphosphate + H+ 6.3.5
6.3.5.M2
–
–
M
(-)-Medicocarpin + malonyl-CoA <=> (-)-medicarpin-3-O-glucoside-6''''-malonate + CoA 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase
–
MK
malonyl-CoA + pantetheine <=> Malonyl_pantetheine + CoA 2.3.1.39 [acyl-carrier-protein] S-malonyltransferase
–
malonyl-CoA + H2O <=> malonate + CoA 3.1.2.1 acetyl-CoA hydrolase
3.1.2.17 (S)-methylmalonyl-CoA hydrolase
3.1.2.18 ADP-dependent short-chain-acyl-CoA hydrolase
3.1.2.19 ADP-dependent medium-chain-acyl-CoA hydrolase
3.1.2.2 palmitoyl-CoA hydrolase
3.1.2.20 acyl-CoA hydrolase
–
–
–
–
–
–
butyryl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ <=> palmitate + (n+1)_CoA + n CO2 + 2n NADP+ 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
octanoyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ <=> palmitate + (n+1)_CoA + n CO2 + 2n NADP+ 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> 6-hydroxymellein + CoA + CO2 + NADP+ + H2O 2.3.1
–
M
malonyl-CoA + NADPH + H+ <=> 3-oxopropanoyl-CoA + NADP+ + H2O not assigned
 –
K
stearoyl-CoA + malonyl-CoA + 2 NADPH + 2 H+ <=> arachidoyl-CoA + CO2 + 2 NADP+ + CoA + H2O not assigned
 –
malonyl-CoA + 6 methylmalonyl-CoA + 6 NADPH + 6 H+ <=> 8,8a-deoxyoleandolide + 7 CoA + 7 CO2 + H2O + 6 NADP+ not assigned
 –
K
2-methylbutanoyl-CoA + 5 methylmalonyl-CoA + 7 malonyl-CoA + 9 NADPH + 9 H+ <=> 6,8a-Seco-6,8a-deoxy-5-oxoavermectin_''''2a''''_aglycone + 12 CO2 + 13 CoA + 5 H2O + 9 NADP+ not assigned
 –
K
2-methylbutanoyl-CoA + 5 methylmalonyl-CoA + 7 malonyl-CoA + 9 NADPH + 9 H+ <=> 6,8a-Seco-6,8a-deoxy-5-oxoavermectin_''''1a''''_aglycone + 12 CO2 + 13 CoA + 6 H2O + 9 NADP+ not assigned
 –
K
isobutyryl-CoA + 5 methylmalonyl-CoA + 7 malonyl-CoA + 9 NADPH + 9 H+ <=> 6,8a-Seco-6,8a-deoxy-5-oxoavermectin_''''2b''''_aglycone + 12 CO2 + 13 CoA + 5 H2O + 9 NADP+ not assigned
 –
K
isobutyryl-CoA + 5 methylmalonyl-CoA + 7 malonyl-CoA + 9 NADPH + 9 H+ <=> 6,8a-Seco-6,8a-deoxy-5-oxoavermectin_''''1b''''_aglycone + 12 CO2 + 13 CoA + 6 H2O + 9 NADP+ not assigned
 –
K
acetyl-CoA + 7 malonyl-CoA + [acyl-carrier_protein] <=> 3,5,7,9,11,13,15-Heptaoxo-hexadecanoyl-[acp] + 7 CO2 + 7 CoA 2.3.1
–
K
butyryl-CoA + 7 malonyl-CoA + [acyl-carrier_protein] <=> 3,5,7,9,11,13,15-Heptaoxo-octadecanoyl-[acp] + 7 CO2 + 7 CoA 2.3.1
–
K
Malonamoyl-CoA + 8 malonyl-CoA + [acyl-carrier_protein] <=> 18-Carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[acp] + 8 CO2 + 9 CoA 2.3.1
–
10 malonyl-CoA + [acyl-carrier_protein] <=> 3,5,7,9,11,13,15,17,19-Nonaoxo-eicosanoyl-[acp] + 10 CO2 + 10 CoA 2.3.1
2.3.1.235 tetracenomycin F2 synthase
–
–
K
propionyl-CoA + 9 malonyl-CoA + [acyl-carrier_protein] <=> 3,5,7,9,11,13,15,17,19-nonaoxohenicosanoyl-[acp] + 9 CO2 + 9 CoA 2.3.1
–
K
butyryl-CoA + 9 malonyl-CoA + [acyl-carrier_protein] <=> 3,5,7,9,11,13,15,17,19-Nonaoxo-docosanoyl-[acp] + 9 CO2 + 9 CoA 2.3.1
–
K
9 malonyl-CoA + 11 NADPH + 10 H+ + S-adenosyl-L-methionine + [acyl-carrier_protein] <=> Dihydromonacolin_L-[acyl-carrier_protein] + 9 CoA + 9 CO2 + 11 NADP+ + S-adenosyl-L-homocysteine + 6 H2O 2.3.1.161 lovastatin nonaketide synthase
–
K
glycitin + malonyl-CoA <=> Malonylglycitin + CoA 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase
–
K
pelargonidin_3-O-(6-O-malonyl-beta-D-glucoside) + malonyl-CoA <=> Pelargonidin_3-O-3'''',6''''-O-dimalonylglucoside + CoA 2.3.1
–
K
Delphinidin_3-O-(6''''-O-malonyl)-beta-D-glucoside + malonyl-CoA <=> Delphinidin_3-O-3'''',6''''-O-dimalonylglucoside + CoA 2.3.1
–
K
caffeoyl-CoA + 3 malonyl-CoA <=> 2',3,4,4',6'-pentahydroxychalcone + 4 CoA + 3 CO2 2.3.1.74 chalcone synthase
–
K
feruloyl-CoA + 3 malonyl-CoA <=> homoeriodictyol_chalcone + 4 CoA + 3 CO2 2.3.1.74 chalcone synthase
–
K
4-coumaroyl-CoA + malonyl-CoA + hexanoyl-CoA + H2O <=> (1E,4Z)-5-hydroxy-1-(4-hydroxyphenyl)deca-1,4-dien-3-one + 3 CoA + 2 CO2 not assigned
 –
K
feruloyl-CoA + malonyl-CoA + hexanoyl-CoA + H2O <=> 1-Dehydro-[6]-gingerdione + 3 CoA + 2 CO2 not assigned
 –
K
isobutyryl-CoA + 3 malonyl-CoA <=> 8-Methyl-6-nonenoic_acid not assigned
 –
K
8 malonyl-CoA + [acyl-carrier_protein] <=> 3,5,7,9,11,13,15-Heptaoxo-hexadecanoyl-[acp] + 8 CO2 + 8 CoA 2.3.1
–
K
malonyl-CoA + acyl-CoA <=> 3-oxoacyl-CoA + CoA + CO2 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
acetyl-CoA + 3 malonyl-CoA + [acyl-carrier_protein] <=> Orsellinate-[acp] + 4 CoA + 3 CO2 + H2O 2.3.1
–
K
8 malonyl-CoA + 7 NADPH + 7 H+ + [acyl-carrier_protein] <=> 3-Hydroxyhexadeca-4,6,8,10,12,14-hexaenoyl-[acp] + 8 CoA + 8 CO2 + 6 H2O + 7 NADP+ not assigned
 –
K
2 malonyl-CoA + [acyl-carrier_protein] + 2 NADPH + 2 H+ + S-adenosyl-L-methionine <=> (S)-2-Methylbutanoyl-[acp] + 2 CoA + 2 CO2 + 2 NADP+ + S-adenosyl-L-homocysteine + H2O 2.3.1.244 2-methylbutanoate polyketide synthase
–
K
Malonamoyl-[acyl-carrier_protein] + 8 malonyl-CoA <=> 18-Carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[acp] + 8 CO2 + 8 CoA 2.3.1.260 tetracycline polyketide synthase
–
K
S-Anthraniloyl-L-cysteinyl-protein + malonyl-CoA <=> 2-aminobenzoylacetyl-CoA + CO2 + S-Anthraniloyl-L-cysteinyl-protein 2.3.1.262 anthraniloyl-CoA anthraniloyltransferase
–
K
4-Hydroxybenzoyl-[acp] + 8 malonyl-CoA + 16 NADPH + 16 H+ <=> 17-(4-Hydroxyphenyl)heptadecanoyl-[acp] + 8 CO2 + 8 CoA + 16 NADP+ + 8 H2O 2.3.1.261 (4-hydroxyphenyl)alkanoate synthase
–
4-Hydroxybenzoyl-[acp] + 9 malonyl-CoA + 18 NADPH + 18 H+ <=> 19-(4-Hydroxyphenyl)nonadecanoyl-[acp] + 9 CO2 + 9 CoA + 18 NADP+ + 9 H2O 2.3.1.261 (4-hydroxyphenyl)alkanoate synthase
–
laurate + malonyl-CoA + glycine <=> 4-Keto-2-undecylpyrroline + 2 H2O + 2 CO2 + CoA not assigned
 –
K
Pyrrolyl-2-carboxyl-S-[acyl-carrier_protein] + malonyl-CoA + L-serine <=> 4-Hydroxy-2,2''-bipyrrole-5-methanol + CoA + [acyl-carrier_protein] + 2 CO2 + H2O not assigned
 –
K
malonyl-CoA + acetyl-CoA <=> dodecanoyl-[acyl-carrier_protein] not assigned
 –
K
S-adenosyl-L-methionine + malonyl-CoA + lovastatin_nonaketide_synthase + NADPH + H+ <=> dihydromonacolin_L-[lovastatin_nonaketide_synthase] + S-adenosyl-L-homocysteine + CO2 + CoA + H2O + NADP+ 2.3.1.161 lovastatin nonaketide synthase
–
M
lignoceroyl-[acp_domain_within_a_fatty_acid_synthase] + malonyl-CoA + H+ <=> 3-oxohexacosanoyl-[acp_domain_within_a_fatty_acid_synthase] + CoA + CO2 2.3.1.86 fatty-acyl-CoA synthase system
–
M
stearoyl-CoA + malonyl-CoA <=> behenoyl-CoA + CO2 + CoA not assigned
 –
hexanoyl-CoA + malonyl-CoA + H+ <=> olivetol + CoA + CO2 2.3.1
–
H+ + hexanoyl-CoA + malonyl-CoA <=> 4-hydroxy-6-(2-oxoheptyl)-2H-pyran-2-one + CoA + CO2 2.3.1
–
malonyl-CoA + H+ <=> hexaketide_pyrone + CoA + CO2 + H2O 2.3.1
–
M
malonyl-CoA + H+ <=> heptaketide_pyrone + CoA + CO2 + H2O 2.3.1
–
M
H+ + malonyl-CoA <=> 2,7-dihydroxy-5-[(4-hydroxy-2-oxo-2H-pyran-6-yl)methyl]-2-methyl-2,3-dihydro-4H-chromen-4-one + CoA + CO2 + H2O 2.3.1
–
M
H+ + malonyl-CoA <=> 2,7-dihydroxy-5-[(4-hydroxy-2-oxo-2H-pyran-6-yl)methyl]-5-methyl-2,3-dihydro-4H-chromen-4-one + CoA + CO2 + H2O not assigned
 –
M
acetyl-CoA + malonyl-CoA + NADPH + H+ + O2 <=> hexaketide_pyrone + CO2 + CoA + H2O + NADP+ 2.3.1
–
acetyl-CoA + malonyl-CoA + NADPH + H+ + O2 <=> 1,8-dihydroxy-3-methylnaphthalene + CO2 + CoA + NADP+ + H2O 2.3.1
–
M
S-adenosyl-L-methionine + (2-hydroxybenzoyl)adenylate + L-cysteine + malonyl-CoA + NADPH + H+ <=> yersiniabactin + CoA + S-adenosyl-L-homocysteine + NADP+ + H2O + AMP 2.3.1
–
M
acetyl-CoA + malonyl-CoA + H2O + H+ <=> 3,5,7,9,11,13,15,17,19-nonaoxoicosanoate + CoA + CO2 not assigned
 –
M
hydroxyacyl-CoA + malonyl-CoA + H+ <=> hydroxylated_tetraketide_alpha-pyrone + CO2 + CoA not assigned
 –
RS-CH2-CH(NH3+)COO- + malonyl-CoA <=> N-malonyl-L-cysteine-S-conjugate + CoA + H+ 2.3.1
–
M
2-naphthyl-beta-D-glucopyranoside + malonyl-CoA <=> 2-naphthol_6''-O-malonylglucoside + CoA 2.3.1
–
M
naphthalen-1-yl_beta-D-glucopyranoside + malonyl-CoA <=> 1-naphthol_6''-O-malonylglucoside + CoA 2.3.1
–
M
4-methylumbelliferyl_glucoside + malonyl-CoA <=> 4-methylumbelliferone_6''-O-malonylglucoside + CoA 2.3.1
–
M
malonyl-CoA + gamma-linolenoyl-CoA + H+ <=> 3-oxodihomo_gamma-linolenoyl-CoA + CoA + CO2 2.3.1
–
M
palmitoyl-[acyl-carrier_protein] + malonyl-CoA <=> 1-heptadecene + CO2 + [acyl-carrier_protein] + CoA 2.3.1
–
heptodecanoyl-[acp] + malonyl-CoA + H+ + reduced_acceptor <=> 1-octadecene + CO2 + [acyl-carrier_protein] + CoA + acceptor 2.3.1
–
acyl-[acyl-carrier_protein] + malonyl-CoA + reduced_acceptor + H+ <=> terminal_olefin + CO2 + [acyl-carrier_protein] + CoA + acceptor 2.3.1
–
M
stearoyl-[acyl-carrier_protein] + malonyl-CoA + H+ <=> 1-nonadecene + CO2 + [acyl-carrier_protein] + CoA 2.3.1
–
malonyl-CoA + arachidoyl-CoA + H+ <=> 3-oxobehenoyl-CoA + CO2 + CoA 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
M
malonyl-CoA + lignoceroyl-CoA + H+ <=> 3-oxocerotoyl-CoA + CO2 + CoA 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
M
malonyl-CoA + behenoyl-CoA + H+ <=> 3-oxo-lignoceroyl-CoA + CO2 + CoA 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
M
malonyl-CoA + oleoyl-CoA + H+ <=> 3-oxo-eicosenoyl-CoA + CO2 + CoA 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
M
polyketide-[acp] + acetyl-CoA + malonyl-CoA + H+ <=> 3,5,7,9,11,13,15,17,19-nonaoxoicosanoyl-[PKS-acp] + CO2 + CoA 2.3.1
–
M
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> eicosapentaenoic_acid + CO2 + CoA + H2O + NADP+ 2.3.1
–
M
malonyl-CoA + linolenoyl-CoA + H+ <=> (11Z,14Z,17Z)-3-oxoicosatrienoyl-CoA + CoA + CO2 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
M
malonyl-CoA + eicosapentaenoyl-CoA + H+ <=> (5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA + CoA + CO2 2.3.1
–
M
malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> spinosyn_macrolactone + CO2 + CoA + H2O + NADP+ 2.3.1
–
M
hexanoyl-CoA + malonyl-CoA + H+ <=> 3,5-dioxodecanoyl-CoA + CoA + CO2 not assigned
 –
M
3,5-dioxodecanoyl-CoA + malonyl-CoA + H+ <=> 3,5,7-trioxododecanoyl-CoA + CoA + CO2 not assigned
 –
M
malonyl-CoA + ricinoleoyl-CoA + H+ <=> 3-oxo-lesqueroloyl-CoA + CoA + CO2 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
M
propionyl-CoA + malonyl-CoA + polyketide-[acp] + H+ <=> 3,5,7,9,11,13,15,17,19-nonaoxohenicosanoyl-[acp] + CO2 + CoA 2.3.1
–
M
malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> Protomycinolide_IV + CoA + CO2 + H2O + NADP+ 2.3.1
–
M
cyanidin_3-O-[[2-O-beta-D-xylosyl]-6-O-(6-O-(4-coumaroyl)-beta-D-glucoside)]_5-O-beta-D-glucoside + malonyl-CoA <=> cyanidin_3-O-[2-O-(xylosyl)-6-O-(p-coumaroyl)_glucoside]_5-O-malonylglucoside + CoA 2.3.1
–
M
S-adenosyl-L-methionine + malonyl-CoA + holo-2-methylbutanoyl-[polyketide_synthase] + NADPH + H+ <=> (S)-2-methylbutanoyl-[2-methylbutanoate_polyketide_synthase] + S-adenosyl-L-homocysteine + CO2 + CoA + H2O + NADP+ 2.3.1.244 2-methylbutanoate polyketide synthase
–
M
malonyl-CoA + holo-[PigH_polyketide_synthase/acyl-carrier_protein] <=> malonyl-[PigH] + CoA 2.3.1
–
M
acetyl-CoA + malonyl-CoA + [acyl-carrier_protein] + H+ <=> acetoacetyl-[acyl-carrier_protein] + CoA + CO2 2.3.1
–
M
S-adenosyl-L-methionine + malonyl-CoA + acetyl-CoA + [acyl-carrier_protein] + NADPH + H+ <=> 6,8-dimethyl-3-oxo-4,6-decadienoyl-[acp] + S-adenosyl-L-homocysteine + CoA + CO2 + H2O + NADP+ 2.3.1
–
M
S-adenosyl-L-methionine + malonyl-CoA + acetyl-CoA + NADPH + H+ + [acyl-carrier_protein] <=> 10-methyl-3-oxo-4,6,8-dodecatrienoyl-[acp] + NADP+ + CoA + S-adenosyl-L-homocysteine + CO2 + H2O 2.3.1
–
M
S-adenosyl-L-methionine + malonyl-CoA + acetyl-CoA + [acyl-carrier_protein] + NADPH + H+ <=> 8,10-dimethyl-3-oxo-4,6,8-dodecatrienoyl-[acp] + CoA + S-adenosyl-L-homocysteine + CO2 + H2O + NADP+ 2.3.1
–
M
S-adenosyl-L-methionine + acetyl-CoA + malonyl-CoA + NADPH + H+ + [acyl-carrier_protein] <=> 4,6-dimethyl-3-oxooctanoyl-[acp] + NADP+ + CoA + S-adenosyl-L-homocysteine + H2O + CO2 2.3.1
–
M
S-adenosyl-L-methionine + acetyl-CoA + malonyl-CoA + NADH + H+ + [acyl-carrier_protein] <=> 4,6-dimethyl-3-oxooctanoyl-[acp] + NAD+ + CoA + S-adenosyl-L-homocysteine + H2O + CO2 2.3.1
–
4-aminobenzoyl-CoA + malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> candicinolide + CoA + CO2 + H2O + NADP+ 2.3.1
–
M
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> arachidonic_acid + CO2 + CoA + H2O + NADP+ 2.3.1
–
M
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> docosahexaenoic_acid + CO2 + CoA + H2O + NADP+ 2.3.1
–
M
malonyl-CoA + stearidonoyl-CoA + H+ <=> (8Z,11Z,14Z,17Z)-3-oxoicosatetraenoyl-CoA + CoA + CO2 2.3.1
–
M
S-adenosyl-L-methionine + acetyl-CoA + malonyl-CoA <=> 3,5-dimethylorsellinate + S-adenosyl-L-homocysteine + CO2 + CoA 2.3.1
–
M
malonyl-CoA + Arachidonoyl-CoA + H+ <=> (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA + CO2 2.3.1
–
M
malonyl-CoA + (7Z,10Z,13Z,16Z)-Docosatetraenoyl-CoA + H+ <=> (9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA + CoA + CO2 2.3.1
–
M
malonyl-CoA + docosapentaenoyl-CoA + H+ <=> (9Z,12Z,15Z,18Z,21Z)-3-oxotetracosapentaenoyl-CoA + CoA + CO2 2.3.1
–
M
malonyl-CoA + linoleoyl-CoA + H+ <=> (11Z,14Z)-3-oxoicosadienoyl-CoA + CO2 + CoA 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
M
malonyl-CoA + densipoloyl-CoA + H+ <=> 3-oxoauricoloyl-CoA + CoA + CO2 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
M
S-adenosyl-L-methionine + acetyl-CoA + malonyl-CoA + [acyl-carrier_protein] + NADPH + H+ <=> 8,10,16-trimethyl-3-oxooctadeca-4,8,12,14,16-pentaenoyl-[acp] + S-adenosyl-L-homocysteine + CoA + CO2 + NADP+ + H2O 2.3.1
–
M
2,5-dimethyl-4-oxo-4,5-dihydrofuran-3-yl_beta-D-glucopyranoside + malonyl-CoA <=> malonyl-furaneol_glucopyranoside + CoA 2.3.1
–
M
acetyl-CoA + malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> decarboxy-dehydroxy-demycosaminyl-nystatin + CoA + CO2 + H2O + NADP+ 2.3.1
–
M
7-hydroxylauroyl-CoA + malonyl-CoA + H+ <=> 2-(8-hydroxy-2-oxotridecyl)-6-oxopyran-4-olate + CO2 + CoA not assigned
 –
M
acetyl-CoA + malonyl-CoA + [acyl-carrier_protein] + H+ <=> 1-(2,4-dihydroxy-6-methylphenyl)octane-1,3,5,7-tetrone-[acp] + CoA + CO2 + H2O 2.3.1
–
M
Malonamoyl-CoA + malonyl-CoA + [acyl-carrier_protein] + H+ <=> 4-(3-acetyl-2,5,7,10-tetrahydroxy-4-oxo-3-hydroanthracen-2-yl)-3-oxobutanamyl-[acp] + CoA + CO2 + H2O 2.3.1
–
M
acetyl-CoA + malonyl-CoA <=> L-2-aminodecanoate not assigned
 –
M
acetyl-CoA + malonyl-CoA <=> 2-oxooctanoate not assigned
 –
M
S-adenosyl-L-methionine + malonyl-CoA + [acyl-carrier_protein] + NADPH + H+ <=> 1-[(1S,2R,4aS,6R,8aR)-1,6-dimethyl-2-[(1E)-prop-1-en-1-yl)]-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl]butane-1,3-dioyl-[acp] + CoA + S-adenosyl-L-homocysteine + NADP+ + CO2 + H2O 2.3.1
–
M
S-adenosyl-L-methionine + acetyl-CoA + malonyl-CoA + [acyl-carrier_protein] + NADPH + H+ <=> (5E,7E,9E,11E,13E)-3,7,11,13-tetramethylpentadeca-5,7,9,11,13-pentaene-2,4-dioyl-[acp] + CoA + S-adenosyl-L-homocysteine + CO2 + NADP+ + H2O 2.3.1
–
M
S-adenosyl-L-methionine + acetyl-CoA + malonyl-CoA + [acyl-carrier_protein] + NADPH + H+ <=> (5E,7E,9E,11E,13Z)-5,9,11,13-tetramethylpentadeca-5,7,9,11,13-pentaene-2,4-dioyl-[acp] + CoA + S-adenosyl-L-homocysteine + CO2 + NADP+ + H2O 2.3.1
–
M
S-adenosyl-L-methionine + acetyl-CoA + malonyl-CoA + NADPH + H+ <=> 3-methylorcinaldehyde + S-adenosyl-L-homocysteine + CoA + H2O + NADP+ + CO2 2.3.1
–
M
propanoyl-[acp] + malonyl-CoA + H2O + H+ <=> 3,5,7,9,11,13,15,17,19-nonaoxohenicosanoate + [acyl-carrier_protein] + CoA + CO2 2.3.1
–
acetyl-CoA + malonyl-CoA + [acyl-carrier_protein] + H+ <=> pentadecane-2,4,6,8,10,12,14-heptonyl-[acp] + CoA + CO2 2.3.1
–
M
malonyl-CoA + [acyl-carrier_protein] + H+ <=> nonadecane-2,4,6,8,10,12,14,16,18-nononyl-[acp] + CoA + CO2 2.3.1
–
M
guanidinoacetyl-[polyketide_synthase] + aminomalonyl-[L-seryl-carrier_protein] + malonyl-CoA + L-glutamate + NADPH + H+ <=> (2S,3S,7R)-2-amino-3-amino-7-hydroxy-8-(2-iminoimidazolidin-4-yl)octanoyl-[GdnH_polyketide_synthase] + CoA + 2-oxoglutarate + holo-[L-seryl-carrier_protein] + CO2 + H2O + NADP+ 2.3.1
–
M
fatty_acid + L-asparagine + L-serine + malonyl-CoA + aminomalonyl-[L-seryl-carrier_protein] + (2R)-2-hydroxymalonyl-[acp] + L-Albizziin + L-alanine + O2 + NADPH + H+ + polyketide-[acp] <=> proto-zwittermicin_A-L-alanyl-[PKS] + CO2 + NADP+ + H2O + holo-[L-seryl-carrier_protein] + [acyl-carrier_protein] + CoA 2.3.1
–
M
acetyl-CoA + malonyl-CoA + [acyl-carrier_protein] + H+ <=> 3,5,7,9,11,13-hexaoxotetradecanoyl-[acp] + CoA + CO2 2.3.1
–
M
S-adenosyl-L-methionine + malonyl-CoA + acetyl-CoA + [acyl-carrier_protein] + NADPH + H+ <=> (5E,7S,9S,11,E,13E,15E)-7,9,15-trimethylheptadeca-5,11,13,15-tetraene-2,4-dionyl-[acp] + CoA + S-adenosyl-L-homocysteine + CO2 + NADP+ + H2O 2.3.1
–
M
S-adenosyl-L-methionine + malonyl-CoA + acetyl-CoA + [acyl-carrier_protein] + NADH + H+ <=> (5E,7S,9S,11,E,13E,15E)-7,9,15-trimethylheptadeca-5,11,13,15-tetraene-2,4-dionyl-[acp] + CoA + S-adenosyl-L-homocysteine + CO2 + NAD+ + H2O 2.3.1
–
heptanoyl-CoA + malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> C32-mycoketide-CoA + CoA + CO2 + NADP+ + H2O 2.3.1.295 mycoketide-CoA synthase
–
behenoyl-[(phenol)carboxyphthiodiolenone_synthase] + malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> C34-carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone_synthase] + NADP+ + H2O + CO2 + CoA 2.3.1.292 (phenol)carboxyphthiodiolenone synthase
–
M
arachidoyl-[(phenol)carboxyphthiodiolenone_synthase] + malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> C32-carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone_synthase] + CoA + CO2 + H2O + NADP+ 2.3.1.292 (phenol)carboxyphthiodiolenone synthase
–
4-hydroxybenzoyl-[4-hydroxyphenylalkanoate_synthase] + malonyl-CoA + NADPH + H+ <=> 19-(4-hydroxyphenyl)nonadecanoyl-[4-hydroxyphenylalkanoate_synthase] + CoA + CO2 + NADP+ + H2O 2.3.1.261 (4-hydroxyphenyl)alkanoate synthase
–
M
a_long-chain_acyl-[(phenol)carboxyphthiodiolenone_synthase] + malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone_synthase] + NADP+ + H2O + CO2 + CoA 2.3.1.292 (phenol)carboxyphthiodiolenone synthase
–
medium-chain_fatty_acyl-CoA + malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> a_mycoketide-CoA + CoA + CO2 + NADP+ + H2O 2.3.1.295 mycoketide-CoA synthase
–
M
[PqsD_protein]-S-anthraniloyl-L-cysteine + malonyl-CoA + H+ <=> 2-aminobenzoylacetyl-CoA + CO2 + [PqsD_protein]-L-cysteine not assigned
 –
M
(S)-2-methylbutanoyl-CoA + malonyl-CoA + H+ <=> 2-methyl-1-[2,4,6-trihydroxy-3-(3-methylbut-2-en-1-yl)phenyl]butan-1-one + CO2 + CoA 2.3.1.156 phloroisovalerophenone synthase
–
M
acetyl-CoA + malonyl-CoA + H+ + holo-[ArmB_polyketide_synthase] <=> orsellinyl-[armB_polyketide_synthase] + CoA + CO2 + H2O not assigned
 –
M
acetyl-CoA + malonyl-CoA + 1,4,5,10,13-pentahydroxy-Delta2,3-protoilludene + H+ <=> melledonol + CO2 + CoA + H2O 2.3.1.M46
–
acetyl-CoA + malonyl-CoA + 1,4,5-trihydroxy-Delta2,3-protoilludene + H+ <=> melleolide_F + CoA + CO2 + H2O 2.3.1.M46
–
acetyl-CoA + malonyl-CoA + H2O + H+ <=> orsellinic_acid + CoA + CO2 + H2O 2.3.1.M46
–
M
4,5-dichloro-1H-pyrrole-2-carbonyl-[PltL_prolyl-carrier_protein] + malonyl-CoA + NADPH + H+ <=> 7-(4,5-dichloro-1H-pyrrol-2-yl)-3-hydroxy-5,7-dioxoheptanoyl-[PltL_prolyl-carrier_protein] + CoA + NADP+ + CO2 2.3.1
–
M
caffeoyl-CoA + malonyl-CoA + H+ <=> hispidin + CO2 + CoA 2.3.1.M47
–
holo-[aureothin_polyketide_synthase] + 4-nitrobenzoyl-CoA + malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> (8E,10E)-2,4,8,10-tetramethyl-11-(4-nitrophenyl)-3,5-dioxoundeca-8,10-dienoyl-[aureothin_polyketide_synthase] + CO2 + CoA + NADP+ + H2O not assigned
 –
M
holo-[spectinabilin_polyketide_synthase] + 4-nitrobenzoyl-CoA + (S)-methylmalonyl-CoA + malonyl-CoA + NADPH + H+ <=> (2Z,4Z,8E,10E,12E,14E)-3,5-dihydroxy-2,4,8,10,12,14-hexamethyl-15-(4-nitrophenyl)pentadeca-2,4,8,10,12,14-hexaenoyl-[spectinabilin_polyketide_synthase] + CO2 + CoA + NADP+ + H2O not assigned
 –
M
3-amino-5-hydroxybenzoyl-[streptovaricin_PKS] + (S)-methylmalonyl-CoA + malonyl-CoA + NADPH + H+ <=> tetraketide-[streptovaricin_PKS] + CoA + NADP+ + CO2 2.3.1
–
M
7-(5-amino-3,6-dioxocyclohexa-1,4-dien-1-yl)-7-hydroxy-2,6-dimethyl-3,5-dioxoheptanoyl-[streptovaricin_PKS] + (S)-methylmalonyl-CoA + malonyl-CoA + NADPH + H+ <=> undecaketide-[streptovaricin-PKS] + CoA + NADP+ + CO2 + H2O not assigned
 –
M
7-(5-amino-3,6-dioxocyclohexa-1,4-dien-1-yl)-7-hydroxy-2,6-dimethyl-3,5-dioxoheptanoyl-[chaxamycin_PKS] + (S)-methylmalonyl-CoA + malonyl-CoA + NADPH + H+ <=> undecaketide-[chaxamycin-PKS] + CoA + NADP+ + CO2 + H2O 2.3.1
–
M
3-amino-5-hydroxybenzoyl-[chaxamycin_PKS] + (S)-methylmalonyl-CoA + malonyl-CoA + NADPH + H+ <=> tetraketide-[chaxamycin_PKS] + CoA + NADP+ + CO2 2.3.1
–
M
7-(5-amino-3,6-dioxocyclohexa-1,4-dien-1-yl)-7-hydroxy-2,6-dimethyl-3,5-dioxoheptanoyl-[naphthomycin_PKS] + (S)-methylmalonyl-CoA + malonyl-CoA + NADPH + H+ <=> tetradecaketide-[naphthomycin-PKS] + CoA + NADP+ + CO2 + H2O 2.3.1
–
M
3-amino-5-hydroxybenzoyl-[naphthomycin_PKS] + (S)-methylmalonyl-CoA + malonyl-CoA + NADPH + H+ <=> tetraketide-[naphthomycin_PKS] + CoA + NADP+ + CO2 2.3.1
–
M
3-amino-5-hydroxybenzoyl-[ansatrienin_PKS] + (S)-methylmalonyl-CoA + malonyl-CoA + NADPH + H+ <=> nonaketide-[ansatrienin_PKS] + CoA + NADP+ + CO2 + H2O 2.3.1.M77
–
M
malonyl-CoA + hexacosanoyl-CoA + H+ <=> 3-oxooctacosanoyl-CoA + CO2 + CoA 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
M
malonyl-CoA + octacosanoyl-CoA + H+ <=> 3-oxotriacontanoyl-CoA + CO2 + CoA 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
M
malonyl-CoA + melissoyl-CoA + H+ <=> 3-oxodotriacontanoyl-CoA + CO2 + CoA 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
M
malonyl-CoA + dotriacontanoyl-CoA + H+ <=> 3-oxotetratriacontanoyl-CoA + CO2 + CoA 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
M
malonyl-CoA + tetratriacontanoyl-CoA + H+ <=> 3-oxohexatriacontanoyl-CoA + CO2 + CoA 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
M
malonyl-CoA + erucoyl-CoA + H+ <=> (15Z)-3-oxotetracos-15-enoyl-CoA + CO2 + CoA 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
M
malonyl-CoA + eicosenoyl-CoA + H+ <=> 3-oxo-erucoyl-CoA + CO2 + CoA 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
M
malonyl-CoA + (15Z)-tetracosenoyl-CoA + H+ <=> (17Z)-3-oxohexacosenoyl-CoA + CO2 + CoA 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
malonyl-CoA + (6Z,9Z,12Z,15Z,18Z)-Tetracosapentaenoyl-CoA + H+ <=> (8Z,11Z,14Z,17Z,20Z)-3-oxohexacosapentaenoyl-CoA + CO2 + CoA 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
malonyl-CoA + (9Z,12Z,15Z,18Z)-Tetracosatetraenoyl-CoA + H+ <=> (11Z,14Z,17Z,20Z)-3-oxohexacosatetraenoyl-CoA + CO2 + CoA 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
malonyl-CoA + (6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosahexaenoyl-CoA + H+ <=> (8Z,11Z,14Z,17Z,20Z,23Z)-3-oxohexacosahexaenoyl-CoA + CO2 + CoA 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
S-adenosyl-L-methionine + guanidinoacetyl-[polyketide_synthase] + malonyl-CoA + NADPH + H+ <=> (2E)-4-guanidino-2-methyl-but-2-enoyl-[CyrB_PKS] + CO2 + S-adenosyl-L-homocysteine + CoA + H2O + NADP+ 2.3.1
–
M
(2E)-4-guanidino-2-methyl-but-2-enoyl-[CyrB_PKS] + malonyl-CoA + NADPH + H+ <=> (4E,6E,9S,10E)-12-guanidino-9-hydroxy-10-methyl-3-oxododeca-4,6,10-trienoyl-[CyrF_PKS] + CO2 + CoA + H2O + NADP+ 2.3.1
–
M
malonyl-CoA + holo_[BryU_acyl-carrier_protein] <=> CoA + malonyl-[BryU_acyl-carrier_protein] 2.3.1.39 [acyl-carrier-protein] S-malonyltransferase
–
M
malonyl-CoA + holo_[BryP_acyl-carrier_protein] <=> CoA + malonyl-[BryP_acyl-carrier_protein] 2.3.1.39 [acyl-carrier-protein] S-malonyltransferase
–
M
malonyl-CoA + holo_[PedD_acyl-carrier_protein] <=> CoA + malonyl-[PedD_acyl-carrier_protein] 2.3.1.39 [acyl-carrier-protein] S-malonyltransferase
–
M
malonyl-CoA + holo_[PedN_acyl-carrier_protein] <=> CoA + malonyl[PedN_acyl-carrier_protein] 2.3.1.39 [acyl-carrier-protein] S-malonyltransferase
–
M
malonyl-CoA + 3beta,14beta,21-trihydroxy-5beta-pregnane-20-one <=> 3beta,14beta-dihydroxy-5beta-pregnane-20-one-21-O-malonylhemiester + CoA 2.3.1
–
M
cinnamoyl-CoA + chalcone_synthase + malonyl-CoA + H+ <=> (8E)-3,5,7-trioxo-9-phenylnon-8-enoyl-[chalcome_synthase] + CoA + CO2 not assigned
 –
M
cinnamoyl-CoA + malonyl-CoA + polyketide-[acp] + H+ <=> (6E)-3,5-dioxo-7-phenylhept-6-enoyl-[styrylpyrone_synthase] + CO2 + CoA not assigned
 –
M
4-coumaroyl-CoA + malonyl-CoA + H+ + polyketide-[acp] <=> (6E)-7-(4-hydroxyphenyl)-3,5-dioxohept-6-enoyl-[styrylpyrone_synthase] + CoA + CO2 not assigned
 –
M
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> 7-methylmellein + CoA + CO2 + H2O + NADP+ 2.3.1.M91
–
M
malonyl-CoA + myristoyl-D-asparaginyl-L-alanyl-[ClbB_polyketide_synthase] + NADPH + H+ <=> myristoyl-D-asparaginyl-butan-2-aminyl-acetyl-[ClbB_polyketide_synthase] + CoA + CO2 + H2O + NADP+ not assigned
 –
M
holo_[ClbC_polyketide_synthase] + myristoyl-D-asparaginyl-butan-2-aminyl-acetyl-[ClbB_polyketide_synthase] + malonyl-CoA + H+ <=> myristoyl-D-asparaginyl-butan-2-aminyl-malonyl-[ClbC_polyketide_synthase] + holo_[ClbB_polyketide_synthase] + CO2 + CoA not assigned
 –
M
myristoyl-D-asparaginyl-butan-2-aminyl-malonyl-1-aminocyclopropane-1-carboxyl-[ClbH_non-ribosomal_peptide_synthase] + malonyl-CoA + holo_[ClbI_polyketide_synthase] + H+ <=> myristoyl-D-asparaginyl-butan-2-aminyl-malonyl-1-aminocyclopropane-1-carboxyl-acetyl-[ClbI_polyketide_synthase] + holo_[ClbH_non-ribosomal_peptide_synthase] + CO2 + CoA not assigned
 –
M
malonyl-CoA + H+ <=> laccaate_anthrone + CoA + CO2 + H2O not assigned
 –
polyketide-[acp] + malonyl-CoA + H+ <=> [pks]-atrochrysone_thioester + CoA + CO2 + H2O 2.3.1
–
M
stearoyl-[acp_domain_within_a_fatty_acid_synthase] + malonyl-CoA + H+ <=> 3-oxoicosanoyl-[acp_domain_within_a_fatty_acid_synthase] + CO2 + CoA 2.3.1.86 fatty-acyl-CoA synthase system
–
M
icosanoyl-[acp_domain_within_a_fatty_acid_synthase] + malonyl-CoA + H+ <=> 3-oxodocosanoyl-[acp_domain_within_a_fatty_acid_synthase] + CO2 + CoA 2.3.1.86 fatty-acyl-CoA synthase system
–
M
acetyl-CoA + malonyl-CoA + H+ <=> aloesone + CoA + CO2 + H2O 2.3.1
–
M
H+ + 4-coumaroyl-CoA + H2O + malonyl-CoA <=> CoA + CO2 + p-coumaroyltriacetate 2.3.1
–
M
malonyl-CoA + very-long-chain_2,3,4-saturated_fatty_acyl_CoA <=> very-long-chain_oxoacyl-CoA + CO2 + CoA 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
M
H+ + 4-coumaroyl-CoA + malonyl-CoA <=> 4-coumaroyltriacetic_acid_lactone + CoA + CO2 2.3.1
–
M
isovaleryl-CoA + malonyl-CoA + H+ <=> 4-hydroxy-6-isobutyl-2-pyrone + CoA + CO2 2.3.1
–
isovaleryl-CoA + malonyl-CoA + H+ <=> 4-hydroxy-6-(4'-methyl-2'-oxopentyl)-2-pyrone + CoA + CO2 2.3.1
–
7-hydroxyflavone_3-O-beta-D-glucoside + malonyl-CoA <=> 7-hydroxyflavone_7-O-(6-malonyl-beta-D-glucoside) + CoA 2.3.1
–
3-amino-5-hydroxybenzoyl-[rifamycin_PKS] + (S)-methylmalonyl-CoA + malonyl-CoA + NADPH + H+ <=> tetraketide-[rifamycin_PKS] + CoA + NADP+ + CO2 2.3.1
–
M
7-(5-amino-3,6-dioxocyclohexa-1,4-dien-1-yl)-7-hydroxy-2,6-dimethyl-3,5-dioxoheptanoyl-[rifamycin_PKS] + (S)-methylmalonyl-CoA + malonyl-CoA + NADPH + H+ <=> undecaketide-[rifamycin-PKS] + CoA + NADP+ + CO2 + H2O not assigned
 –
M
H+ + (9Z,12Z)-hexadeca-9,12,15-trienoyl-CoA + malonyl-CoA <=> 5-pentadecatrienyl_resorcinol + CoA + CO2 2.3.1
–
M
malonyl-CoA + lauroyl-CoA + H+ <=> 3-oxotetradecanoyl-CoA + CO2 + CoA 2.3.1
–
malonyl-CoA + myristoyl-CoA + H+ <=> 3-ketohexadecanoyl-CoA + CO2 + CoA 2.3.1
–
butyryl-[acyl-carrier_protein] + malonyl-CoA + H+ <=> 3-oxohexanoyl-[acyl-carrier_protein] + CO2 + CoA 2.3.1.41 beta-ketoacyl-[acyl-carrier-protein] synthase I
–
M
hexanoyl-[acyl-carrier_protein] + malonyl-CoA + H+ <=> 3-oxooctanoyl-[acyl-carrier_protein] + CO2 + CoA 2.3.1.41 beta-ketoacyl-[acyl-carrier-protein] synthase I
–
M
octanoyl-[acyl-carrier_protein] + malonyl-CoA + H+ <=> 3-oxodecanoyl-[acyl-carrier_protein] + CO2 + CoA 2.3.1.41 beta-ketoacyl-[acyl-carrier-protein] synthase I
–
M
decanoyl-[acyl-carrier_protein] + malonyl-CoA + H+ <=> 3-oxododecanoyl-[acyl-carrier_protein] + CO2 + CoA 2.3.1.41 beta-ketoacyl-[acyl-carrier-protein] synthase I
–
M
dodecanoyl-[acyl-carrier_protein] + malonyl-CoA + H+ <=> 3-oxotetradecanoyl-[acyl-carrier_protein] + CO2 + CoA 2.3.1.41 beta-ketoacyl-[acyl-carrier-protein] synthase I
–
M
tetradecanoyl-[acyl-carrier_protein] + malonyl-CoA + H+ <=> 3-oxohexadecanoyl-[acyl-carrier_protein] + CO2 + CoA 2.3.1.41 beta-ketoacyl-[acyl-carrier-protein] synthase I
–
malonyl-CoA + [a_holo_malonate_decarboxylase_acyl-carrier-protein] <=> CoA + malonyl-[holo_malonate_decarboxylase_acyl-carrier_protein] 2.3.1
–
M
acetyl-CoA + [carboxyl-carrier_protein_dimer]-N6-carboxybiotinyl-L-lysine <=> malonyl-CoA + [biotin_carboxyl-carrier-protein_dimer]-N6-biotinyl-L-lysine 2.1.3.15 acetyl-CoA carboxytransferase
–
M
malonyl-CoA + polyketide-[acp] + H+ <=> 3,5,7,9,11,13,15-hepta-oxo-hexadecanoyl-[PKS-acp] + CO2 + CoA 2.3.1
–
M
docosanoyl-[acp_domain_within_a_fatty_acid_synthase] + malonyl-CoA + H+ <=> 3-oxotetracosanoyl-[acp_domain_within_a_fatty_acid_synthase] + CO2 + CoA 2.3.1.86 fatty-acyl-CoA synthase system
–
M
malonyl-CoA + holo-[RedN_acyl-carrier_protein/polyketide_synthase] <=> malonyl-[RedN] + CoA 2.3.1
–
M
malonyl-CoA + RedL_polyketide_synthase <=> malonyl-[RedL_polyketide_synthase] + CoA 2.3.1
–
M
palmitoyl-[acp_domain_within_a_fatty_acid_synthase] + malonyl-CoA + H+ <=> 3-oxooctadecanoyl-[acp_domain_within_a_fatty_acid_synthase] + CO2 + CoA 2.3.1.86 fatty-acyl-CoA synthase system
–
M
malonyl-CoA + acetyl-[acp_domain_within_a_fatty_acid_synthase] + H+ <=> acetoacetyl-[acp_domain_within_a_fatty_acid_synthase] + CoA + CO2 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
M
butanoyl-[acp_domain_within_a_fatty_acid_synthase] + malonyl-CoA + H+ <=> 3-oxohexanoyl-[acp_domain_within_a_fatty_acid_synthase] + CO2 + CoA 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
M
hexanoyl-[acp_domain_within_a_fatty_acid_synthase] + malonyl-CoA + H+ <=> 3-oxooctanoyl-[acp_domain_within_a_fatty_acid_synthase] + CO2 + CoA 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
M
octanoyl-[acp_domain_within_a_fatty_acid_synthase] + malonyl-CoA + H+ <=> 3-oxodecanoyl-[acp_domain_within_a_fatty_acid_synthase] + CO2 + CoA 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
M
decanoyl-[acp_domain_within_a_fatty_acid_synthase] + malonyl-CoA + H+ <=> 3-oxododecanoyl-[acp_domain_within_a_fatty_acid_synthase] + CO2 + CoA 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
M
dodecanoyl-[acp_domain_within_a_fatty_acid_synthase] + malonyl-CoA + H+ <=> 3-oxotetradecanoyl-[acp_domain_within_a_fatty_acid_synthase] + CO2 + CoA 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
M
myristoyl-[acp_domain_within_a_fatty_acid_synthase] + malonyl-CoA + H+ <=> 3-oxohexadecanoyl-[acp_domain_within_a_fatty_acid_synthase] + CO2 + CoA 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
M
acyl-[acp_domain_within_a_fatty_acid_synthase] + malonyl-CoA + H+ <=> 3-oxoacyl-[acp_domain_within_a_fatty_acid_synthase] + CO2 + CoA 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
dATP + acetyl-CoA + HCO3- <=> dADP + phosphate + malonyl-CoA 6.4.1.2 acetyl-CoA carboxylase
–
GTP + acetyl-CoA + HCO3- <=> GDP + phosphate + malonyl-CoA 6.4.1.2 acetyl-CoA carboxylase
–
UTP + acetyl-CoA + HCO3- <=> UDP + phosphate + malonyl-CoA 6.4.1.2 acetyl-CoA carboxylase
–
acetyl-CoA + malonyl-CoA <=> acetoacetyl-CoA + CoA 2.3.1.41 beta-ketoacyl-[acyl-carrier-protein] synthase I
–
acetyl-CoA + malonyl-CoA <=> 6-acetonyl-4-hydroxy-2-pyrone + Triacetate_lactone + CoA + CO2 2.3.1.95 trihydroxystilbene synthase
–
S-adenosyl-L-methionine + malonyl-CoA <=> S-adenosyl-L-homocysteine + malonyl-CoA_methyl_ester 2.1.1.197 malonyl-[acyl-carrier protein] O-methyltransferase
–
malonyl-CoA + 4-coumaroyl-CoA + NADH <=> 6''-deoxychalcone + CoA + CO2 + NAD+ 2.3.1.74 chalcone synthase
–
acetyl-CoA + malonyl-CoA + NADH <=> palmitate + CoA + CO2 + NAD+ 2.3.1.85 fatty-acid synthase system
–
succinyl-CoA + malonate <=> succinate + malonyl-CoA 2.8.3.13 succinate---hydroxymethylglutarate CoA-transferase
–
8 malonyl-CoA + 4 NADPH + 16 H+ <=> 8 CoA + (2E,4E,10E)-15-hydroxyhexadeca-2,4,10-trienoic_acid + 8 CO2 + 4 NADP+ + 6 H2O 2.3.1.B39
–
9 malonyl-CoA + 5 NADPH + 19 H+ <=> 9 CoA + (4E,6Z,12E)-17-hydroxyoctadeca-4,6,12-trienoic_acid + 9 CO2 + 5 NADP+ + 7 H2O 2.3.1.B39
–
8 malonyl-CoA + NADPH + H+ <=> 8 CoA + (4E,6E,8E,10E,12E,14E)-3-hydroxyhexadeca-4,6,8,10,12,14-hexaenoic_acid + 8 CO2 + NADP+ + H2O 2.3.1.B40
–
malonyl-CoA + 4-coumaroyl-CoA + NADPH <=> 5''-deoxyflavanone + CoA + CO2 + NADP+ 2.3.1.74 chalcone synthase
–
propionyl-CoA + malonyl-CoA + NADPH <=> 6-Ethylsalicylic_acid + CoA + CO2 + NADP+ 2.3.1.165 6-methylsalicylic-acid synthase
–
acetyl-CoA + 8 malonyl-CoA + 11 NADPH + S-adenosyl-L-methionine + 11 H+ <=> dihydromonacolin_L + 9 CoA + 8 CO2 + 11 NADP+ + S-adenosyl-L-homocysteine + 6 H2O 2.3.1.161 lovastatin nonaketide synthase
–
acetyl-CoA + malonyl-CoA + [2-methylbutanoate_polyketide_synthase] + 2 NADPH + 2 H+ + S-adenosyl-L-methionine <=> (S)-2-methylbutanoyl-[2-methylbutanoate_polyketide_synthase] + 2 CoA + CO2 + 2 NADP+ + S-adenosyl-L-homocysteine + H2O 2.3.1.244 2-methylbutanoate polyketide synthase
–
2 malonyl-CoA + [2-methylbutanoate_polyketide_synthase] + 2 NADPH + 3 H+ + S-adenosyl-L-methionine <=> (S)-2-methylbutanoyl-[2-methylbutanoate_polyketide_synthase] + 2 CoA + 2 CO2 + 2 NADP+ + S-adenosyl-L-homocysteine + H2O 2.3.1.244 2-methylbutanoate polyketide synthase
–
9 malonyl-CoA + 11 NADPH + 10 H+ + S-adenosyl-L-methionine + holo-[lovastatin_nonaketide_synthase] <=> dihydromonacolin_L-[lovastatin_nonaketide_synthase] + 9 CoA + 9 CO2 + 11 NADP+ + S-adenosyl-L-homocysteine + 6 H2O 2.3.1.161 lovastatin nonaketide synthase
–
acetyl-CoA + malonyl-CoA + NADPH + H+ + S-adenosyl-L-methionine <=> 4-hydroxy-6-[(1E,3E,5E)-1-methylhepta-1,3,5-trien-1-yl]-2H-pyran-2-one + 4-hydroxy-6-[(1E,3E,5E,7E)-3-methylnona-1,3,5,7-tetraen-1-yl]-2H-pyran-2-one + CoA + CO2 + NADP+ + S-adenosyl-L-homocysteine + H2O 2.3.1.161 lovastatin nonaketide synthase
–
acetoacetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ <=> palmitate + (n+1)_CoA + n CO2 + 2n NADP+ 2.3.1.85 fatty-acid synthase system
–
4-hydroxybenzoyl-[4-hydroxyphenylalkanoate_synthase] + 9 malonyl-CoA + 18 NADPH + 18 H+ + holo-[4-hydroxyphenylalkanoate_synthase] <=> 19-(4-hydroxyphenyl)nonadecanoyl-[4-hydroxyphenylalkanoate_synthase] + 9 CO2 + 9 CoA + 18 NADP+ + 9 H2O 2.3.1.261 (4-hydroxyphenyl)alkanoate synthase
–
4-hydroxybenzoyl-[4-hydroxyphenylalkanoate_synthase] + 9 malonyl-CoA + 18 NADPH + 18 H+ + holo-[4-hydroxyphenylalkanoate_synthase] <=> 19-(4-hydroxyphenyl)nonadecanoyl-[4-hydroxyphenylalkanoate_synthase] + 9 CO2 + 9 CoA + 18 NADP+ + 9 H2O 2.3.1.261 (4-hydroxyphenyl)alkanoate synthase
–
hexanoyl-CoA + 5 malonyl-CoA + 5 (S)-methylmalonyl-CoA + 22 NADPH + 22 H+ <=> a_mycoketide-CoA + 10 CO2 + 10 CoA + 22 NADP+ + 11 H2O 2.3.1.295 mycoketide-CoA synthase
–
3 malonyl-CoA + 2 (S)-methylmalonyl-CoA + icosanoyl-[(phenol)carboxyphthiodiolenone_synthase] + 5 NADPH <=> C32-carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone_synthase] + 5 CoA + 5 NADP+ + 5 CO2 + 2 H2O 2.3.1.292 (phenol)carboxyphthiodiolenone synthase
–
3 malonyl-CoA + 2 (S)-methylmalonyl-CoA + docosanoyl-[(phenol)carboxyphthiodiolenone_synthase] + 5 NADPH <=> C34-carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone_synthase] + 5 CoA + 5 NADP+ + 5 CO2 + 2 H2O 2.3.1.292 (phenol)carboxyphthiodiolenone synthase
–
acetoacetyl-CoA + 3 malonyl-CoA + NADPH + H+ <=> Triacetate_lactone + CoA + NADP+ 2.3.1.165 6-methylsalicylic-acid synthase
–
2 cinnamoyl-CoA + malonyl-CoA + H2O <=> 3 CoA + dicinnamoylmethane + 2 CO2 2.3.1.211 bisdemethoxycurcumin synthase
–
cinnamoyl-CoA + malonyl-CoA <=> 5,7-dihydroxyflavanone + CoA + CO2 2.3.1.74 chalcone synthase
–
3-Coumaroyl-CoA + malonyl-CoA <=> 3,3'',5-trihydroxystilbene + CoA + CO2 2.3.1.95 trihydroxystilbene synthase
–
malonyl-CoA + amikacin <=> CoA + N3''-malonyl-amikacin 2.3.1.81 aminoglycoside 3-N-acetyltransferase
–
malonyl-CoA + isorhamnetin_3-O-glucoside <=> CoA + isorhamnetin_3-O-glucoside_malonylester 2.3.1.116 flavonol-3-O-beta-glucoside O-malonyltransferase
–
isorhamnetin_3-O-glucoside + malonyl-CoA <=> CoA + isorhamnetin_3-O-glucoside_6''''-O-malonylester 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase
–
4-hydroxybenzoyl-CoA + 3 malonyl-CoA <=> 2,4,4'',6-trihydroxybenzophenone + 4 CoA + 3 CO2 2.3.1.151 2,3',4,6-tetrahydroxybenzophenone synthase
–
malonyl-CoA + 1-aminocyclopropane-1-carboxylate <=> CoA + malonyl-1-aminocyclopropan-1-carboxylic_acid 2.3.1.112 D-tryptophan N-malonyltransferase
–
N-hydroxy-L-ornithine + malonyl-CoA <=> N5-acetyl-N5-hydroxyornithine + CoA + CO2 4.1.1.9 malonyl-CoA decarboxylase
–
malonyl-CoA + malvidin_3-O-beta-D-glucoside <=> CoA + malvidin_3-O-(6-O-malonyl-beta-D-glucoside) 2.3.1.171 anthocyanin 6''-O-malonyltransferase
2.3.1.215 anthocyanidin 3-O-glucoside 6''-O-acyltransferase
–
–
malonyl-CoA + neomycin <=> CoA + N3-malonylneomycin_B 2.3.1.81 aminoglycoside 3-N-acetyltransferase
–
palmitoyl-[acyl-carrier_protein] + malonyl-CoA <=> 3-oxooctadecanoyl-[acyl-carrier_protein] + CO2 + CoA 2.3.1.41 beta-ketoacyl-[acyl-carrier-protein] synthase I
–
B
malonyl-CoA + malvin <=> CoA + malvidin_3-O-beta-D-glucoside_5-O-(6-O-malonyl)-beta-D-glucoside 2.3.1.153 anthocyanin 5-(6'''-hydroxycinnamoyltransferase)
2.3.1.172 anthocyanin 5-O-glucoside 6'''-O-malonyltransferase
–
–
malonyl-CoA + adipate <=> malonate + adipyl-CoA 2.8.3.13 succinate---hydroxymethylglutarate CoA-transferase
–
malonyl-CoA + 2,4-dichloroaniline <=> CoA + N-(2,4-dichlorophenyl)-malonamate 2.3.1.114 3,4-dichloroaniline N-malonyltransferase
–
malonyl-CoA + 3-chloroaniline <=> CoA + N-(3-chlorophenyl)-malonamate 2.3.1.114 3,4-dichloroaniline N-malonyltransferase
–
4-methoxycinnamoyl-CoA + 3 malonyl-CoA <=> 4-methoxy-2'',4'',6''-trihydroxychalcone + CoA + CO2 2.3.1.159 acridone synthase
–
malonyl-CoA + 3'-dephospho-CoA <=> CoA + malonyl-dephospho-CoA 2.1.3.10 malonyl-S-ACP:biotin-protein carboxyltransferase
2.3.1.187 acetyl-S-ACP:malonate ACP transferase
–
–
malonyl-CoA + 5-aminosalicylic_acid <=> CoA + N-malonyl-5-aminosalicylate 2.3.1.5 arylamine N-acetyltransferase
–
4-fluorocinnamoyl-CoA + malonyl-CoA <=> 4''-fluoro-trans-3,5-dihydroxystyrylfuran + CoA + CO2 2.3.1.95 trihydroxystilbene synthase
–
malonyl-CoA + kaempferol_7-O-glucoside <=> CoA + kaempferol_7-O-glucoside_6''''-O-malonylester 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase
–
malonyl-CoA + 2-chloroaniline <=> CoA + N-(2-chlorophenyl)-malonamate 2.3.1.114 3,4-dichloroaniline N-malonyltransferase
–
malonyl-CoA + 2-Aminophenol <=> CoA + N-malonyl-2aminophenol 2.3.1.5 arylamine N-acetyltransferase
–
malonyl-CoA + 2-hydroxy-amino-6-methyldipyrido[1,2-a:_3'',2''-d]imidazole <=> CoA + N-malonyloxyamino-6-methyldipyrido[1,2-a:_3'',2''-d]imidazole 2.3.1.118 N-hydroxyarylamine O-acetyltransferase
–
malonyl-CoA + petunidin_3-O-beta-D-glucoside <=> CoA + petunidin_3-O-(6-O-malonyl-beta-D-glucoside) 2.3.1.171 anthocyanin 6''-O-malonyltransferase
–
pentanoyl-CoA + malonyl-CoA <=> 6-butyl_triacetic_acid_lactone + CoA 2.3.1.165 6-methylsalicylic-acid synthase
–
malonyl-CoA + methylmalonate <=> malonate + methylmalonyl-CoA 2.8.3.13 succinate---hydroxymethylglutarate CoA-transferase
2.8.3.3 malonate CoA-transferase
–
–
acetoacetyl-CoA + 2 malonyl-CoA <=> Triacetate_lactone + CoA + CO2 + H2O 2.3.1.233 1,3,6,8-tetrahydroxynaphthalene synthase
–
acetoacetyl-CoA + malonyl-CoA <=> Triacetate_lactone + CoA 2.3.1.165 6-methylsalicylic-acid synthase
–
malonyl-CoA + gentamicin <=> CoA + N3''-malonyl-gentamicin 2.3.1.81 aminoglycoside 3-N-acetyltransferase
–
malonyl-CoA + shisonin <=> CoA + 6''''''-malonylshisonin 2.3.1.172 anthocyanin 5-O-glucoside 6'''-O-malonyltransferase
–
malonyl-CoA + 4-nitrophenyl-beta-D-glucopyranoside <=> CoA + p-nitrophenyl_6-O-malonyl-beta-D-glucopyranoside 2.3.1.116 flavonol-3-O-beta-glucoside O-malonyltransferase
–
trans-3-(3-thienyl)acryloyl-CoA + malonyl-CoA <=> trans-3,5-dihydroxystyrylthiophene + CoA + CO2 2.3.1.95 trihydroxystilbene synthase
–
trans-3-furanacryloyl-CoA + malonyl-CoA <=> trans-3,5-dihydroxystyrylfuran + CoA + CO2 2.3.1.95 trihydroxystilbene synthase
–
malonyl-CoA + biochanin_A_7-O-beta-D-glucopyranoside <=> CoA + biochanin_A_7-O-glucoside-6''''-O-malonylester 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase
–
butyryl-CoA + malonyl-CoA <=> bisnoryangonin-type_and_p-coumaroyltriacetic_acid_lactone-type_pyrones + CoA + CO2 2.3.1.95 trihydroxystilbene synthase
–
malonyl-CoA + butyryl-CoA <=> Phlorobutyrophenone + CO2 + CoA 2.3.1.74 chalcone synthase
–
3 malonyl-CoA + butyryl-CoA <=> 4 CoA + 2,4,6-trihydroxybutyrophenone + 6-propyl-4-hydroxy-2-pyrone + 3 CO2 2.3.1.220 2,4,6-trihydroxybenzophenone synthase
–
butyryl-CoA + malonyl-CoA <=> 6-propyl_triacetic_acid_lactone + CoA 2.3.1.165 6-methylsalicylic-acid synthase
–
oleoyl-CoA + malonyl-CoA <=> CoA + 3-oxo-eicosenoyl-CoA + 3-oxo-erucoyl-CoA + CO2 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
malonyl-CoA + 4-Aminophenol <=> CoA + N-(phenyl)-malonamate 2.3.1.114 3,4-dichloroaniline N-malonyltransferase
–
malonyl-CoA + N-acetylcysteamine <=> CoA + N-acetyl-S-malonylcysteamine 2.3.1.39 [acyl-carrier-protein] S-malonyltransferase
–
malonyl-CoA + 2-aminobenzoyl-CoA <=> 2 CoA + 4-hydroxyquinolin-2(1H)-one + CO2 2.3.1.230 2-heptyl-4(1H)-quinolone synthase
–
malonyl-CoA + 4-chloroaniline <=> CoA + N-(4-chlorophenyl)-malonamate 2.3.1.114 3,4-dichloroaniline N-malonyltransferase
–
Luteolin_7-O-glucoside + malonyl-CoA <=> CoA + luteolin_7-O-glucoside_6''''-O-malonylester 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase
–
malonyl-CoA + 3-hydroxybenzoyl-CoA <=> 2 CoA + 2-oxabicyclo[4.3.1]deca-1(10),6,8-triene-3,5-dione + CO2 2.3.1.208 4-hydroxycoumarin synthase
–
malonyl-CoA + 3-hydroxybenzoyl-CoA <=> CoA + 2,3'',4,5-tetrahydroxybenzophenone + CO2 2.3.1.151 2,3',4,6-tetrahydroxybenzophenone synthase
–
malonyl-CoA + 3-hydroxybenzoyl-CoA <=> CoA + 3-hydroxycoumarin 2.3.1.177 3,5-dihydroxybiphenyl synthase
–
propionyl-CoA + malonate <=> malonyl-CoA + propionate 2.8.3.3 malonate CoA-transferase
–
malonyl-CoA + 2-hydroxybenzoyl-CoA <=> CoA + 2-hydroxybenzoyltriacetic_acid_lactone + CO2 2.3.1.177 3,5-dihydroxybiphenyl synthase
–
malonyl-CoA + cyanidin_3-O-[[2-O-beta-D-xylosyl]-6-O-(6-O-(4-coumaroyl)-beta-D-glucoside)]_5-O-beta-D-glucoside <=> CoA + cyanidin_3-O-[[2-O-beta-D-xylosyl]-6-O-(6-O-(4-coumaroyl)-beta-D-glucoside)]_5-O-(6-O-malonyl)-beta-D-glucoside 2.3.1.172 anthocyanin 5-O-glucoside 6'''-O-malonyltransferase
–
malonyl-CoA + cyanidin_3-O-[[2-O-(2-O-sinapoyl)-beta-D-xylosyl]-6-O-(6-O-(4-coumaroyl)-beta-D-glucoside)]_5-O-beta-D-glucoside <=> CoA + cyanidin_3-O-[[2-O-(2-O-sinapoyl)-beta-D-xylosyl]-6-O-(6-O-(4-coumaroyl)-beta-D-glucoside]_5-O-(6-O-malonyl)-beta-D-glucoside 2.3.1.172 anthocyanin 5-O-glucoside 6'''-O-malonyltransferase
–
malonyl-CoA + L-carnitine <=> malonyl-L-carnitine + CoA 2.3.1.137 carnitine O-octanoyltransferase
–
malonylcarnitine + CoA <=> malonyl-CoA + L-carnitine 2.3.1.7 carnitine O-acetyltransferase
–
quercetin_3-O-alpha-D-glucopyranoside + malonyl-CoA <=> CoA + quercetin_3-O-glucoside_6''''-O-malonylester 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase
–
malonyl-CoA + 2,5-dichloroaniline <=> CoA + N-(2,5-dichlorophenyl)-malonamate 2.3.1.114 3,4-dichloroaniline N-malonyltransferase
–
malonyl-CoA + 3,5-dichloroaniline <=> CoA + N-(3,5-dichlorophenyl)-malonamate 2.3.1.114 3,4-dichloroaniline N-malonyltransferase
–
malonyl-CoA + L-homoserine <=> CoA + psychosine_sulfate 2.3.1.31 homoserine O-acetyltransferase
–
propionyl-CoA + malonyl-CoA <=> 6-ethyl_triacetic_acid_lactone + CoA 2.3.1.165 6-methylsalicylic-acid synthase
–
heptanoyl-CoA + malonyl-CoA <=> 6-hexyl_triacetic_acid_lactone + CoA 2.3.1.165 6-methylsalicylic-acid synthase
–
diosmetin_7-O-glucoside + malonyl-CoA <=> CoA + diosmetin_7-O-glucoside_6''''-O-malonylester 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase
–
malonyl-CoA + orobol_7-O-glucoside <=> CoA + orobol_7-O-glucoside_6''''-O-malonylester 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase
–
malonyl-CoA + pratensein_7-O-glucoside <=> CoA + pratensein_7-O-glucoside_6''''-O-malonylester 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase
–
quercetagetin_7-O-glucoside + malonyl-CoA <=> CoA + quercetagetin_7-O-glucoside_6''''-O-malonylester 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase
–
stearoyl-[acyl-carrier_protein] + malonyl-CoA <=> 3-oxoeicosanoyl-[acyl-carrier_protein] + CO2 + CoA 2.3.1.41 beta-ketoacyl-[acyl-carrier-protein] synthase I
–
octanoyl-CoA + malonyl-CoA <=> 4-hydroxy-6-(2'',4'',6''-trioxotridecyl)-2-pyrone + CoA + CO2 + H2O 2.3.1.233 1,3,6,8-tetrahydroxynaphthalene synthase
–
malonyl-CoA + octanoyl-CoA <=> 6-heptyl-4-hydroxy-2-pyrone + CoA + CO2 2.3.1.74 chalcone synthase
–
malonyl-CoA + octanoyl-CoA <=> 1-(2,4,6-trihydroxyphenyl)-octan-1-one + CoA + CO2 2.3.1.74 chalcone synthase
–
malonyl-CoA + 3,4,5-trichloroaniline <=> CoA + N-(3,4,5-trichloro-phenyl)-malonamate 2.3.1.114 3,4-dichloroaniline N-malonyltransferase
–
apiin + malonyl-CoA <=> apigenin_7-O-apiosylglucoside_-6''''-O-malonylester + malonyl-CoA 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase
–
malonyl-CoA + malonate <=> malonyl-CoA + malonate 2.8.3.3 malonate CoA-transferase
–
benzoyl-CoA + malonyl-CoA <=> 2,3'',4,6-tetrahydroxybenzophenone + CoA + CO2 2.3.1.159 acridone synthase
–
3 malonyl-CoA + benzoyl-CoA <=> 4 CoA + benzophenone + 3 CO2 2.3.1.159 acridone synthase
–
benzoyl-CoA + malonyl-CoA <=> bisnoryangonin-type_and_p-coumaroyltriacetic_acid_lactone-type_pyrones + CoA + CO2 2.3.1.95 trihydroxystilbene synthase
–
malonyl-CoA + benzoyl-CoA <=> CoA + 6-phenyl-4-hydroxy-2-pyrone + CO2 2.3.1.151 2,3',4,6-tetrahydroxybenzophenone synthase
2.3.1.220 2,4,6-trihydroxybenzophenone synthase
2.3.1.233 1,3,6,8-tetrahydroxynaphthalene synthase
–
–
–
3 malonyl-CoA + benzoyl-CoA <=> 4 CoA + 2,4,6-trihydroxybenzophenone + 4-hydroxy-6-(2-oxo-2-phenylethyl)-2H-pyran-2-one + 6-phenyl-4-hydroxy-2-pyrone + 3 CO2 2.3.1.151 2,3',4,6-tetrahydroxybenzophenone synthase
–
3 malonyl-CoA + hexanoyl-CoA <=> 4 CoA + phloroglucinol + 3 CO2 2.3.1.159 acridone synthase
–
malonyl-CoA + hexanoyl-CoA <=> Phlorocaprophenone + CO2 + CoA 2.3.1.74 chalcone synthase
–
hexanoyl-CoA + malonyl-CoA <=> bisnoryangonin-type_and_p-coumaroyltriacetic_acid_lactone-type_pyrones + CoA + CO2 2.3.1.95 trihydroxystilbene synthase
–
3 malonyl-CoA + hexanoyl-CoA <=> 4 CoA + 4-hydroxy-6-pentyl-2H-pyran-2-one + 4-hydroxy-6-(2-oxoheptyl)-2H-pyran-2-one + 3 CO2 2.3.1.220 2,4,6-trihydroxybenzophenone synthase
–
3 malonyl-CoA + hexanoyl-CoA <=> 4 CoA + 4-hydroxy-6-pentyl-2H-pyran-2-one + 5-hexanoyl-4-hydroxy-6-methyl-2H-pyran-2-one + 3 CO2 2.3.1.151 2,3',4,6-tetrahydroxybenzophenone synthase
–
hexanoyl-CoA + malonyl-CoA <=> 6-pentyl_triacetic_acid_lactone + CoA 2.3.1.165 6-methylsalicylic-acid synthase
–
malonyl-CoA + phenyl_beta-D-glucoside <=> CoA + phenyl_6-O-malonyl-beta-D-glucopyranoside 2.3.1.116 flavonol-3-O-beta-glucoside O-malonyltransferase
–
crotonyl-CoA + malonyl-CoA <=> 6-(2-propene)_triacetic_acid_lactone + CoA 2.3.1.165 6-methylsalicylic-acid synthase
–
feruloyl-CoA + malonyl-CoA <=> homoeriodictyol + CoA + CO2 2.3.1.74 chalcone synthase
–
feruloyl-CoA + malonyl-CoA + H2O <=> 2 CoA + vanillylidenacetone + 2 CO2 2.3.1.212 benzalacetone synthase
–
2 feruloyl-CoA + malonyl-CoA + H2O <=> 3 CoA + curcumin + 2 CO2 2.3.1.211 bisdemethoxycurcumin synthase
–
feruloyl-CoA + malonyl-CoA <=> 3,4'',5-trihydroxy-3''-methoxystilbene + CoA + CO2 2.3.1.95 trihydroxystilbene synthase
–
feruloyl-CoA + malonyl-CoA <=> rhapontigenin + CoA + CO2 2.3.1.146 pinosylvin synthase
–
2 feruloyl-CoA + malonyl-CoA + H2O <=> 3 CoA + 4-hydroxy-6-[(E)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]-2H-pyran-2-one + curcumin 2.3.1.211 bisdemethoxycurcumin synthase
–
4-coumaroyl-CoA + cinnamoyl-CoA + malonyl-CoA + H2O <=> 3 CoA + cinnamoyl-4-coumaroyl-methane + 2 CO2 2.3.1.211 bisdemethoxycurcumin synthase
–
4-coumaroyl-CoA + malonyl-CoA <=> cis-2-acetylresveratrol + CoA + CO2 2.3.1.146 pinosylvin synthase
–
4-coumaroyl-CoA + malonyl-CoA <=> 2-malonylresveratrol + CoA + CO2 2.3.1.146 pinosylvin synthase
–
malonyl-CoA + 4-coumaroyl-CoA <=> CoA + naringenin_chalcone 2.3.1.159 acridone synthase
2.3.1.74 chalcone synthase
–
–
3 malonyl-CoA + 4-coumaroyl-CoA <=> 4 CoA + resveratrol 2.3.1.95 trihydroxystilbene synthase
–
4-coumaroyl-CoA + malonyl-CoA <=> 4-coumaroyltriacetic_acid_lactone 2.3.1.74 chalcone synthase
–
butyryl-CoA + malonate <=> malonyl-CoA + Butyrate 2.8.3.3 malonate CoA-transferase
–
3 malonyl-CoA + N-methylanthraniloyl-CoA <=> 4 CoA + 1,3-dihydroxy-N-methylacridone + N-methylanthraniloyltriacetic_acid_lactone + 4-hydroxy-1,3-dimethyl-2(1H)-quinolone + 3 CO2 2.3.1.159 acridone synthase
–
N-methylanthraniloyl-CoA + malonyl-CoA <=> N-methylacridone + CoA + CO2 2.3.1.159 acridone synthase
–
2-(3,4-dihydroxyphenyl)-3-[[6-O-[(2E)-3-[4-(beta-D-glucopyranosyloxy)phenyl]prop-2-enoyl]-beta-D-glucopyranosyl-(1-6)-[beta-D-xylopyranosyl-(1-2)]-beta-D-glucopyranosyl]oxy]-7-hydroxychromenium-5-yl_beta-D-glucopyranoside + malonyl-CoA <=> 5-[[6-O-(carboxyacetyl)-beta-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-7-hydroxychromenium-3-yl_6-O-[(2E)-3-[4-(beta-D-glucopyranosyloxy)phenyl]prop-2-enoyl]-beta-D-glucopyranosyl-(1-6)-[beta-D-xylopyranosyl-(1-2)]-beta-D-glucopyranoside + CoA 2.3.1.153 anthocyanin 5-(6'''-hydroxycinnamoyltransferase)
–
2 malonyl-CoA + 2 stearoyl-CoA <=> 6-heptadecyl-4-hydroxy-2H-pyran-2-one + 4-hydroxy-6-(2-oxononadecyl)-2H-pyran-2-one + 2 CoA + 2 CO2 2.3.1.74 chalcone synthase
–
caffeoyl-CoA + 3 malonyl-CoA <=> eriodictyol + 4 CoA + 3 CO2 2.3.1.74 chalcone synthase
–
caffeoyl-CoA + malonyl-CoA <=> 3,3'',4'',5-tetrahydroxystilbene + CoA + CO2 2.3.1.146 pinosylvin synthase
2.3.1.95 trihydroxystilbene synthase
–
–
decanoyl-CoA + malonyl-CoA <=> 1-(2,4,6-trihydroxyphenyl)-decan-1-one + CoA + CO2 2.3.1.74 chalcone synthase
–
malonyl-CoA + Glutarate <=> malonate + glutaryl-CoA 2.8.3.13 succinate---hydroxymethylglutarate CoA-transferase
–
malonyl-CoA + [acyl-carrier_protein] <=> CoA + a_methylmalonyl-[acyl-carrier_protein] 2.3.1.B32
–
2-(3,4-dihydroxyphenyl)-3-[[6-O-[(2E)-3-[4-(beta-D-glucopyranosyloxy)phenyl]prop-2-enoyl]-beta-D-glucopyranosyl-(1-6)-[2-O-[(2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoyl]-beta-D-xylopyranosyl-(1-2)]-beta-D-glucopyranosyl]oxy]-7-hydroxychromenium-5-yl_beta-D-glucopyranoside + malonyl-CoA <=> 5-[[6-O-(carboxyacetyl)-beta-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-7-hydroxychromenium-3-yl_6-O-[(2E)-3-[4-(beta-D-glucopyranosyloxy)phenyl]prop-2-enoyl]-beta-D-glucopyranosyl-(1-6)-[2-O-[(2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoyl]-beta-D-xylopyranosyl-(1-2)]-beta-D-glucopyranoside + CoA 2.3.1.153 anthocyanin 5-(6'''-hydroxycinnamoyltransferase)
–
cyanidin_3,5-di-O-beta-D-glucoside + malonyl-CoA <=> cyanidin_3-O-beta-D-glucoside_5-O-(6-O-malonyl)-beta-D-glucoside + CoA 2.3.1.153 anthocyanin 5-(6'''-hydroxycinnamoyltransferase)
2.3.1.172 anthocyanin 5-O-glucoside 6'''-O-malonyltransferase
–
–
2-oxoisovalerate + malonyl-CoA + H2O <=> 2-hydroxy-3-metylbutane-11,2-tricarboxyl_acid + CoA 2.3.3.13 2-isopropylmalate synthase
–
malonyl-CoA + kaempferol_3-O-glucoside <=> CoA + kaempferol_3-O-glucoside_malonylester 2.3.1.116 flavonol-3-O-beta-glucoside O-malonyltransferase
–
kaempferol_3-O-glucoside + malonyl-CoA <=> CoA + kaempferol_3-O-glucoside_6''''-O-malonylester 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase
–
malonyl-CoA + L-glutamate_5-semialdehyde <=> CoA + (2S,5S)-5-carboxymethylproline + CO2 2.3.1.226 carboxymethylproline synthase
–
naringenin_7-O-glucoside + malonyl-CoA <=> CoA + naringenin_7-O-glucoside_6''''-O-malonylester 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase
–
isovaleryl-CoA + malonyl-CoA <=> bisnoryangonin-type_and_p-coumaroyltriacetic_acid_lactone-type_pyrones + CoA + CO2 2.3.1.95 trihydroxystilbene synthase
–
malonyl-CoA + kanamycin_A <=> CoA + N3''-malonylkanamycin_A 2.3.1.81 aminoglycoside 3-N-acetyltransferase
–
dihydro-4-coumaroyl-CoA + malonyl-CoA <=> 3,4'',5-trihydroxybibenzyl + CoA + CO2 2.3.1.95 trihydroxystilbene synthase
–
Isorhamnetin_7-O-glucoside + malonyl-CoA <=> CoA + isorhamnetin_7-O-glucoside_6''''-O-malonylester 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase
–
3 malonyl-CoA + isobutyryl-CoA <=> 4 CoA + 2,4,6-trihydroxyisobutyrophenone + 3 CO2 2.3.1.220 2,4,6-trihydroxybenzophenone synthase
–
malonyl-CoA + 4-bromoaniline <=> CoA + N-(4-bromophenyl)-malonamate 2.3.1.114 3,4-dichloroaniline N-malonyltransferase
–
S-anthraniloyl-L-cysteinyl-[PqsD_protein] + malonyl-CoA <=> 2-aminobenzoylacetyl-CoA + CO2 + L-cysteinyl-[PqsD_protein] 2.3.1.262 anthraniloyl-CoA anthraniloyltransferase
–
B
malonyl-CoA + 2'',4,4''-trihydroxychalcone_4-O-glucoside <=> CoA + 2'',4,4''-trihydroxychalcone_4-O-glucoside_6''''-O-malonylester 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase
–
malonyl-CoA + 2,3,4,5-tetrachloroaniline <=> CoA + N-(2,3,4,5-tetrachlorophenyl)-malonamate 2.3.1.114 3,4-dichloroaniline N-malonyltransferase
–
malonyl-CoA + 2,3,4-trichloroaniline <=> CoA + N-(2,3,4-trichlorophenyl)-malonamate 2.3.1.114 3,4-dichloroaniline N-malonyltransferase
–
malonyl-CoA + 2,4,5-trichloroaniline <=> CoA + N-(2,4,5-trichlorophenyl)-malonamate 2.3.1.114 3,4-dichloroaniline N-malonyltransferase
–
malonyl-CoA + N-(N-acetyl-beta-alanyl)cysteamine <=> CoA + N-(N-acetyl-beta-alanyl)-S-malonylcysteamine 2.3.1.39 [acyl-carrier-protein] S-malonyltransferase
–
malonyl-CoA + tobramycin <=> CoA + N6''-malonyltobramycin 2.3.1.82 aminoglycoside 6'-N-acetyltransferase
–
(9Z,12Z)-octadec-9,12-dienoyl-CoA + malonyl-CoA <=> (11Z,14Z)-3-oxoeicosa-11,14-dienoyl-CoA + CO2 + CoA 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
(9Z,12Z,15Z)-octadeca-9,12,15-trienoyl-CoA + malonyl-CoA <=> (11Z,14Z,17Z)-3-oxoeicosa-11,14,17-trienoyl-CoA + CO2 + CoA 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
malonyl-CoA + glycetein_7-O-glucoside <=> CoA + glycetein_7-O-glucoside_6''''-O-malonylester 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase
–
quercetin-7-O-glucoside + malonyl-CoA <=> CoA + quercetin_7-O-glucoside_6''''-O-malonylester 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase
–
malonyl-CoA + phenylacetyl-CoA <=> 2,4,6-trihydroxyphenylbenzylketone + CoA + CO2 2.3.1.159 acridone synthase
2.3.1.220 2,4,6-trihydroxybenzophenone synthase
2.3.1.74 chalcone synthase
–
–
–
3 malonyl-CoA + phenylacetyl-CoA <=> 4 CoA + 4-hydroxy-6-(2-oxo-3-phenylpropyl)-2H-pyran-2-one + 6-benzyl-4-hydroxy-2H-pyran-2-one + 2,4,6-trihydroxyphenylbenzylketone + 3 CO2 2.3.1.151 2,3',4,6-tetrahydroxybenzophenone synthase
–
malonyl-CoA + 4-Aminobenzoic_acid <=> CoA + N-malonyl-4-aminobenzoate 2.3.1.5 arylamine N-acetyltransferase
–
malonyl-CoA + peonidin_3-O-beta-D-glucoside <=> CoA + peonidin_3-O-(6-O-malonyl-beta-D-glucoside) 2.3.1.171 anthocyanin 6''-O-malonyltransferase
–
malonyl-CoA + (S)-2-amino-7-oxoheptanoic_acid <=> CoA + (2S,7S)-7-(carboxymethyl)-azepane-2-carboxylic_acid + CO2 2.3.1.226 carboxymethylproline synthase
–
malonyl-CoA + 4-nitroaniline <=> CoA + N-(4-nitrophenyl)-malonamate 2.3.1.114 3,4-dichloroaniline N-malonyltransferase
–
palmitoleoyl-CoA + malonyl-CoA <=> (11Z)-3-oxooctadec-11-enoyl-CoA + CO2 + CoA 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase
–
2 malonyl-CoA <=> acetoacetyl-CoA + CoA + 2 CO2 2.3.1.194 acetoacetyl-CoA synthase
–
4 malonyl-CoA <=> 4 CoA + Triacetate_lactone + 3 CO2 2.3.1.151 2,3',4,6-tetrahydroxybenzophenone synthase
–
16 malonyl-CoA + 28 H+ <=> 16 CoA + 2,7-dihydroxy-5-[(4-hydroxy-2-oxo-2H-pyran-6-yl)methyl]-2-methyl-2,3-dihydro-4H-chromen-4-one + 2,7-dihydroxy-5-[(4-hydroxy-2-oxo-2H-pyran-6-yl)methyl]-5-methyl-2,3-dihydro-4H-chromen-4-one + 16 CO2 + 16 H2O 2.3.1.B25
–
malonyl-CoA + 7-amino-4-methylcoumarin <=> N-(4-methylcoumaryl)-7-malonamate 2.3.1.114 3,4-dichloroaniline N-malonyltransferase
–
acetyl-CoA + malonyl-CoA <=> triacetic_lactone 2.3.1.165 6-methylsalicylic-acid synthase
–
malonyl-CoA + benzoyl-CoA <=> 4-hydroxy-6-[(E)-2-(4-hydroxyphenyl)ethenyl]-2H-pyran-2-one + 4-coumaroyl_triacetic_acid_lactone 2.3.1.74 chalcone synthase
–
malonyl-CoA + 4-fluorocinnamoyl-CoA <=> fluorinated_chalcone + alpha-pyrone 2.3.1.74 chalcone synthase
–
ATP + malonate + CoA <=> ADP + phosphate + malonyl-CoA 6.2.1.9 malate---CoA ligase
–
NAD+ + oxaloacetate + CoA <=> CO2 + malonyl-CoA + NADH 1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
–